The secondary structure of guide RNA molecules fromTrypanosoma brucei
نویسندگان
چکیده
منابع مشابه
The secondary structure of guide RNA molecules from Trypanosoma brucei.
RNA editing in kinetoplastid organisms is a mitochondrial RNA processing phenomenon that is characterized by the insertion and deletion of uridine nucleotides into incomplete mRNAs. Key molecules in the process are guide RNAs which direct the editing reaction by virtue of their primary sequences in an RNA-RNA interaction with the pre-edited mRNAs. To understand the molecular details of this rea...
متن کاملDifferent Trypanosoma brucei guide RNA molecules associate with an identical complement of mitochondrial proteins in vitro.
RNA editing is a mitochondrial transcript maturation process which evolved in kinetoplastid protozoa. It entails the insertion and deletion of exclusively uridine nucleotides directed by gRNAs into pre-mRNAs. Other participating components are not currently known. The aim of this study was to identify mitochondrial proteins that are in direct physical contact with gRNAs thereby possibly involve...
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RNAs are important elements in the metabolism of all organisms. The function of many RNAs is crucially dependent on their structure. Secondary structure is one of the most important factors determining 3d-structure, and functions. Having a more in-depth knowledge about the secondary structure of RNAs would provide researchers a better insight for understanding their functionality. In the last t...
متن کاملRNA secondary structure diagrams for very large molecules: RNAfdl
SUMMARY There are many programs that can read the secondary structure of an RNA molecule and draw a diagram, but hardly any that can cope with 10(3) bases. RNAfdl is slow but capable of producing intersection-free diagrams for ribosome-sized structures, has a graphical user interface for adjustments and produces output in common formats. AVAILABILITY AND IMPLEMENTATION Source code is availabl...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1995
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/23.16.3093